Frequently Asked Questions
What is Paremyd®?
- Paremyd® (hydroxyamphetamine hydrobromide / tropicamide ophthalmic solution) 1% / 0.25%, is a prescription topical mydriatic combination product for ophthalmic use.
What are the features and benefits of Paremyd®?
- For routine diagnostic procedures and in conditions where short-term pupil dilation is desired
- Onset of action within 15 minutes, with maximum effect within 60 minutes
- Recovery beginning at 90 minutes and complete in 6 to 8 hours for most patients
- Combines the effects of the adrenergic agent, hydroxyamphetamine hydrobromide, and the anticholinergic agent, tropicamide
- One-drop formulation provides ease of administration
- Provides clinically significant mydriasis with partial cycloplegia
What is Paremyd® indicated for?
- Paremyd® Solution is indicated for mydriasis in routine diagnostic procedures and in conditions where short-term pupil dilation is desired. Paremyd® provides clinically significant mydriasis with partial cycloplegia.
How is Paremyd® dosed and administered?
- One to two drops in the conjunctival sac. The onset of action with Paremyd® Solution occurs within 15 minutes followed by maximum effect within 60 minutes. Clinically significant dilation, inhibition of pupillary light response, and partial cycloplegia last 3 hours.
- Mydriasis will reverse spontaneously with time, typically in 6 to 8 hours. However, in some cases, complete recovery may take up to 24 hours.
What are the ingredients of Paremyd®?
- Actives: Hydroxyamphetamine hydrobromide, USP 1.0%, Tropicamide, USP 0.25%;
- Preservative: Benzalkonium Chloride 0.005%;
- Inactives: Edetate Disodium 0.015%, Sodium Chloride; Hydrochloric Acid and/or Sodium Hydroxide may be added to adjust pH (4.2 to 5.8 during its shelf life), and Purified Water. The osmolality of Paremyd® is approximately 307 mOsm/L.
How is Paremyd® packaged?
- Paremyd® (hydroxyamphetamine hydrobromide/tropicamide ophthalmic solution) 1% / 0.25% as a 15 mL solution in a 15 mL opaque white, low density polyethylene bottle with a natural low density polyethylene dropper tip and a red polypropylene cap.
- NDC# 17478-704-12
- Sold in eaches
How is Paremyd® used in specific populations?
- Pregnancy: Pregnancy Category C. Animal reproduction studies have not been conducted with Paremyd®. It is also not known whether Paremyd® can cause fetal harm when administered to a pregnant woman or can affect reproduction capability. Paremyd® should be given to a pregnant woman only if clearly needed.
- Nursing Mothers: It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Paremyd® is administered to a nursing woman.
- Pediatric Use: Safety and effectiveness in pediatric patients have not been established. Paremyd® may rarely cause CNS disturbances which may be dangerous in infants and children. Psychotic reactions, behavioral disturbances and vasomotor or cardio-respiratory collapse in children have been reported with the use of anticholinergic drugs. Keep this and all medications out of the reach of children.
- Geriatric Use: No overall differences in safety or effectiveness have been observed between elderly and younger patients.
What important safety information should I know about Paremyd®?
- Paremyd® solution should not be used in patients with angle closure glaucoma or in those with narrow angles in whom dilation of the pupil may precipitate an attack of angle-closure glaucoma.
- This product is also contraindicated in patients who are hypersensitive to any of its components.
How should Paremyd® be stored?
- Store at 20° to 25°C (68° to 77°F)
- Protect from light